Benadryl for cats

Is Benadryl Safe For Cats? (Warning!)

Whenever we human beings have a sneezing or running nose, watery eyes, itchiness, rashes, hives or any other form of allergies, we normally just take some Benadryl to counter the effects of the allergies. Human beings are not the only species susceptible to allergies, but even other species like cats also suffer from allergies. In the same way people take Benadryl when suffering from allergies; do you believe there is Benadryl for cats which when administered to the cats will relieve their allergy?


If you want to find out, please continue reading this article. At times your cat may show some symptoms of allergies, and I know you always wonder if you can give it some Benadryl to ease it from all the discomfort. Wonder no more because we have covered your back, everything that you might need to know about Benadryl and cats has been thoroughly addressed below.

What You Need To Know About Benadryl

The Benadryl brand drug was released in the year 1946. It has an active ingredient known as diphenhydramine. Diphenhydramine deals with histamines since it is an anti-histamine. The histamines which it deals with are such as the inflammatory biochemical which is responsible for causing swellings, skin redness; increased heart beat rate, pain and low blood pressure. Benadryl prevents the symptoms of these allergies.

What Is The Reason For Using Benadryl On Your Cats?

In case your cat is suffering from allergic reactions, vaccine reactions, bug bites or itchiness, Benadryl can easily ease its discomfort. Also, if you decide to take your cat with you for trips over long distances, Benadryl can be an appropriate mild sedative.

Benadryl is an appropriate motion-sickness or anti-nausea medication. An alternative medication could be better if you are treating nausea and motion sickness.

Benadryl for cats

Which Form of Benadryl Is Best For Cats?

Benadryl is availed in different forms. We have the capsules which are in quantities of 25 and 50 milligrams. A chewable tablet of 12.5 milligrams is also available. The most suitable form of Benadryl for cats is the syrup. The reason why it is highly recommended is that it is easily measurable for a precise dosage due to its existence in liquid form and trust me, getting a cat to swallow or eat a pill is difficult enough. It is, therefore, advisable to always go for the syrup form of Benadryl.

Always store the Benadryl at room temperature in a container which is tightly sealed.

How To Administer Benadryl To Your Cat

For a cat of average size, you can administer a tablet of 25 milligrams. A cat with a weight of ten pounds can have a dosage of 4 milliliters of Benadryl with a concentration of 12.5mg/5ml. That is the recommended dosage by most veterinary officers.

Many cats will certainly resist taking their dosage of Benadryl especially if the taste or odor is not pleasant. In such a situation, you can flavor the liquid with fish, chicken or any other approved taste for cats to lure it into taking the medication. You can do this, or you can get it done in a compounding pharmacy. Another way of getting your feline to take the medication is by mixing it up in their food, and probably it will just easily consume the food with no resistance.

Administering the medication is easier using a syringe when administering Benadryl which is in a liquid form. Cat Health Guide insists on administering 2mg in every 8 hours per body pound. For instance, if your cat’s weight is 5 pounds, the right dosage for the feline is 10 milligrams for every dose. The best time to administer the dose is right before your cat is exposed to the cause of the itchiness.

Probable Side-Effects of Benadryl To Your Feline

The same way human beings can suffer some side effects after taking some medication is the same way your cat could suffer from some side effects. This should not alarm you because it only means that the medication is effective and is doing its job in trying to fight your cat’s allergy. The following are some of the side effects that you should expect from your cat after administering it with Benadryl.

  • Drowsiness
  • Strong anti-nausea
  • ​Hyperactivity
  • ​Loss of appetite
  • Diarrhea
  • ​Vomiting
  • ​Sedation
  • Decreased urination
  • Dry mouth

Always try your level best not to overdose your cat. Clearly follow the given instructions regarding how to administer Benadryl to your pet cat. In case of an overdose your cat can have these symptoms;

  • Breathing difficulties
  • Seizures
  • Coma
  • Death

Effectiveness of Benadryl

Benadryl is quite effective in eliminating the symptoms of allergies in kitties. Even if the effectiveness of Benadryl in animals is not as strong as in human beings, it still works approximately one hour after it has been administered to the cat. On the worst side, a whole week or several weeks can elapse before its effects are noticed. Within that period, the cat is likely to be very drowsy, actually too drowsy to scratch or lick.

Is Benadryl Safe For Cats

Precautions to Consider When Administering Benadryl to your Cat

The main reason why you might be administering Benadryl to your cat is because you love it and you don’t want her to feel uncomfortable because of allergies. To be able to use Benadryl safely and efficiently, you need to take some precautionary measures that will help in ensuring that your loved pet cat survives the situation and remains alive to keep you happy and entertained. The following are some of the major precautionary measures every cat lover must take before administering Benadryl to their cats.

  • If your feline takes any tranquilizer, do not administer any Benadryl to her.
  • Ensure that the Benadryl antihistamine that you give your kitty has nothing else but diphenhydramine which is an active ingredient.
  • ​The Benadryl that you give to your kitty should have regular strength with no extra diphenhydramine.
  • ​Always consult your veterinarian when you intend to administer Benadryl to your furbaby just to be sure that the dosage will not affect her negatively whether or not she is taking some other medication. This is the list of drugs which Benadryl can react with so make sure that you don’t administer them to your cat if you plan on using Benadryl on your cat.

- Amitraz

- Selegiline

- Epinephrine

- Depressants of the Central Nervous System

- Furazolidone

- Warfarin sodium

- Heparin calcium or sodium

  • In case your kitty has quite some severe reactions with issues such as breathing difficulties just consult your vet other than just administering some Benadryl to try and eliminate the symptom.
  • Be sure that the medication will not mask a more complicated issue. The Benadryl can heal the symptom, but the underlying problem will remain.
  • ​Be cautious when administering Benadryl to felines with heart problems, bladder disorders, hyperthyroidism or high blood pressure and pregnant cats.
  • In the case of a missed dose, give it as soon as you can. If it is almost the time to administer the other dose, you should skip the already missed dose then get back to the regular schedule. Giving the kitty two doses at the same time is not allowed.


It is alright to give your cat Benadryl but in small doses for a shorter period of time. Even though Benadryl has not been approved for veterinary use by FDA, this particular drug is relatively safe when administered to both cats and dogs. As a matter of fact, a majority of veterinarians administer Benadryl to cats suffering from allergic symptoms. Always remember to consult a veterinarian before you administer any dosage of Benadryl to your feline.

Sarah Keene

I’m Sarah Keene, and I’m glad you found your way to my blog. I love cats so much; I consider myself a cat woman. I have 5 cats at the moment, and I am planning to grow my cat family. It is not easy to take care of these cats appropriately though I would wish to make them feel as comfortable as possible. This is why I depend on other blogging cat lovers like me to help me in providing all the necessities for my cats to have the best life possible.

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harvey cook - last month

our vet prescribed Apoquel for our cats allergy and severe stratching, however, i read the side affects and thought i would try Benadryl instead. How long of a time would we give it? 5 days? Or until sores and itch went away? He has been suffering with this for two years. Had tests, many treatments, so this is our most recent attempt to help him. Thank you.

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